Molecular mechanisms in the pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis
نویسندگان
چکیده
منابع مشابه
Ameliorative effect of silibinin against N-nitrosodimethylamine-induced hepatic fibrosis in rats.
The protective effect of silibinin (SBN) against hepatic fibrosis induced by repeated intermittent administration of N-nitrosodimethylamine (DMN) was investigated in rats. Oral administration of SBN recovered body and liver weight loss and reversed the elevation of serum AST, ALT and ALP accompanied by their fall in the liver tissue in DMN-induced fibrotic rats. Severe oxidative stress induced ...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2019
ISSN: 2041-4889
DOI: 10.1038/s41419-018-1272-8